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DNA replication, recombination and repair
Enzyme mechanism and technology; Protein structure, folding and dynamics
Glycobiology
Lipid and membrane biology
Bioinformatics and systems biology
Personalized medicine and diagnostics
Agriculture biotechnology
Synthetic biology
Molecular medicine and drug discovery
Antibody therapeutics
Cell signaling and molecular basis of diseases
Bioentrepreneurship : from science to business
Translational research
New and emerging subjects
Epigenetics and stem cells


DNA Replication, Recombination, and Repair

WEDNESDAY, OCTOBER 22
10:50-12:50
ZVI LIVNEH
DNA Damage Tolerance in Mammals: New Methods and New Genes Leading to Mechanistic Insights and Links to Disease
Weizmann Institute of Science, Israel

Uncovering Polymerase-induced Cytotoxicity of an Oxidized Nucleotide
SAMUEL WILSON
National Institute of Health, USA

DNA Translesion Synthesis: Catalysis and Mechanism to Bypass Roadblocks
WEI YANG
National Institute of Health, USA

Ribonucleotides in DNA: Origins, Repair and Consequences
THOMAS KUNKEL
National Institute of Health, USA


THURSDAY, OCTOBER 23
15:45-17:45
Structural Landscape of Phospho-dependent Interactions in the Cell-cycle and DNA-damage Response
STEVE SMERDON
MRC National Institute for Medical Research, UK

Mdm2 Phosphorylation by the Checkpoint Kinase TTK/hMps1 Promotes Oxidative DNA Damage Response and Repair Through Histone H2B Ubiquitination
SHEAU-YANN SHIEH
Academia Sinica, Taiwan

The Cell Cycle Regulated Initiation Mechanism of Chromosomal DNA Replication in Budding Yeast
HIROYUKI ARAKI
National Institute of Genetics, Japan

The Ribosome Is Involved in Cell Fate Determination and Virulence in Candida albicans
JOON KIM
EMBO YIP; University of Oxford, UK


SATURDAY, OCTOBER 25
10:50-12:50
The Mechanistic Action of SWI5-SFR1 Complex on RAD51-mediated Recombination
PETER CHI
National Taiwan University, Taiwan

Control of DNA Repair Activity at Mammalian Telomeres
JACQUELINE JACOBS
EMBO YIP; The Netherlands Cancer Institute, the Netherlands

Segmental Aneuploidy in Trichoderma Reesei Meiosis Enhances Production of Hemicellulases
TING-FANG WANG
Academia Sinica, Taiwan

Molecular Insights into Meiotic Chromosome Pairing from Single Molecule Analysis
K. MUNIYAPPA
Indian Institute of Science Bangalore, India



 

Enzyme Mechanism and Technology, Protein Structure, Folding, and Dynamics

WEDNESDAY, OCTOBER 22
10:50-12:50
From Genes to Enzymes to Compounds. Evolution of Function in the Isoprenoid Biosynthetic Pathway
C. DALE POULTER
University of Utah, USA

Discovering Novel Enzymes and Metabolic Pathways
JOHN GERLT
Discovering Novel Enzymes and Metabolic Pathways

Mechanisms of Oxygen Activation by Flavin-Dependent enzymes
PIMCHAI CHAIYEN
Mdhidol University, Thailand

Revealing the Structural Changes in the Process of the α-to-β Transition of Mouse Prion Protein
PEI-YEH RITA CHEN
Academia Sinica, Taiwan

THURSDAY, OCTOBER 23
15:45-17:45
γ-Peptide Foldamers
YOUNG-KEE KANG
Chungbuk National University, South Korea

Understanding the Unusual Biological Function and Action Mechanism of the Acid Resistant Molecular Chaperone HdeA: from in vitro to in vivo
ZENGYI CHANG
Peking University, China

Supersaturation-limited Protein Misfolding Revealed by Ultrasonication
YUJI GOTO
Osaka University, Japan

Leveraging Structure for Enzyme Function Prediction: Methods, Opportunities and Challenges
MATTHEW P. JACOBSON
University of California, San Francisco, USA

SATURDAY, OCTOBER 25
10:50-12:50
Molecular Basis for mRNA Recognition and Degradation
LIANG TONG
Columbia University, USA

Structural Basis for Specific Aminoacyl-tRNA Synthesis and Genetic Code Expansion
SHIGEYUKI YOKOYAMA
RIKEN, Japan

Regulation of Gene Expression via Nascent Polypeptide-mediated Translation Stalling
DANIEL WILSON
EMBO YIP; Ludwig-Maximilians-Universität München, Germany

Structure of Ybr137wp Involved in the Targeting of Tail-anchored Proteins to ER-membrane
CHWAN-DENG DAVID HSIAO
Academia Sinica, Taiwan


 

Glycobiology

WEDNESDAY, OCTOBER 22
15:45-17:45
High Sensitivity Glycomics: Windows to Glycan Function
ANNE DELL
Imperial College, UK

Peters Plus Syndrome: A Congenital Disorder of Glycosylation Affecting Proteins Containing Thrombospondin Type 1 Repeats
ROBERT HALTIWANGER
Stony Brook University, USA

Systems Glycobiology Approach for Understanding the Role of Glycans in Disease Onset, Biomarker and Therapeutics
NAOYUKI TANIGUCHI
RIKEN, Japan

The Rationales for Targeting Glycans in Cancer Immunotherapy
LIN-TSING ALICE YU
Chang-Gung Memorial Hospital, Taiwan


FRIDAY, OCTOBER 24
10:50-12:50
Glycans at the Interface Between Invasive Streptococcal Pathogens and the Human Host: Molecular Mimicry and Innate Immune Evasion
VICTOR NIZET
University of California, San Diego, USA
Dendritic Cell Migration, Endothelial Cell Infection and T Cell Surface Redox Regulated by Galectin-Glycoprotein Lattices on the Cell Surface
LINDA BAUM
University of California, Los Angeles, USA

Functional Roles of Mucin-type O-glycosylation in Cancer
MIN-CHUAN HUANG
National Taiwan University Hospital, Taiwan

Nanostructured Electrochemical Biosensor for the Detection of the Weak Binding between Dengue Virus and C-type Lectins
SHIE-LIANG EDMOND HSIEH
Academia Sinica, Taiwan



 

Lipid and Membrane Biology

WEDNESDAY, OCTOBER 22
10:50-12:50
Boosting Membrane Fission by Polyunsaturated Phospholipids (or Why is it Good to Eat Omega 3 Lipids)
BRUNO ANTONNY
Université de Nice & CNRS, Frances

Roles for Phospholipid Flippases in Membrane Biogenesis
TODD R. GRAHAM
Vanderbilt University, USA

Targeting Proteins to Lipid Droplets with Amphipathic Helices
CATHY JACKSON
University Paris Diderot, France

Strategies for Converting a Membrane Surface to a High-Resolution Lipid Signaling Screen
VYTAS A. BANKAITIS
Texas A&M University Health Science Center, USA

SATURDAY, OCTOBER 25
10:50-12:50
Recycling Storage Lipids when Cells Enter Quiescence
CHAO-WEN WANG
Academia Sinica, Taiwan

Mechanisms of Fat Synthesis and Storage in Lipid Droplets
TOBIAS WALTHER
Yale University, USA

Intestinal Triacylglycerol Metabolism and Systemic Energy Balance
CHI-LIANG ERIC YEN
The University of Wisconsin-Madiso, USA

Membrane Protein Structure - Function Studies With Lipid Mesophases
MARTIN CAFFREY
Trinity College Dublin, Ireland


 

Bioinformatics and Systems Biology

WEDNESDAY, OCTOBER 22
15:45-17:45
What Are MicroRNAs Good For? -- Analyzing the Stability of Transcriptome As Foodwebs
CHUNG-I WU
University of Chicago, USA

Response Network of Ectopic ATP Synthase Blockade
HSUEH-FEN YUKI JUAN
National Taiwan University, Taiwan

Mining Omics Data Helps Understand Phenotype-Specific Biological Mechanisms
SUN KIM
Seoul National University, Korea

Integrative Approaches for Gene Prioritization and Applications to Disease Clustering
FENGZHU SUN
University of Southern California, USA

THURSDAY, OCTOBER 23
10:20-12:50
A Feedback Loop Between Cell Shape and Division Orientation Promotes Robust Morphogenesis of Developing Epithelia
SEAN G. MEGASON
Harvard Medical School, USA

HSIEN-DA HUANG
Exploring Conformational Change Profile of Proteins
TIEN-HAO CHANG
National Cheng-Kung University, Taiwan

Computer Aided Studies of Stem Cell Epigenetics
JUI-HUNG HUNG
National Chiao-Tung University, Taiwan


 

Personalized Medicine and Diagnostic

WEDNESDAY, OCTOBER 22
15:45-17:45
From Complex Morphoproteomics to Individualized Cares - An Informatics Approach
CHI-REN SHYU
University of Missouri, USA

Quantitative Modeling of Cell-specific miRNA Abundance and Its Application in Cancer
MICHAEL Q. ZHANG
The University of Texas at Dallas, USA

Application of Next-Generation Sequencing to Identify Actionable Mutations and Cancer Driver Genes
ZHONGMING ZHAO
Vanderbilt University, USA

Move Pharmacogenomic Discovery to Medical Practice
YUAN-TSONG CHEN
Academia Sinica, Taiwan

FRIDAY, OCTOBER 24
10:50-12:50
In Situ Cardiac Regeneration and Rejuvenation by Endogenous Stem Cells
PATRICK C. H. HSIEH

Cancer Metastasis Revisited: Pros and Cons of Platelets and Natural Killer Cells
DANIEL CHAN
University of Colorado, Anschutz Medical Oncology, USA

Recurrent Inactivation of PRC2 in Malignant Peripheral Nerve Sheath Tumors
WILLIAM LEE
Memorial Sloan-Kettering Cancer Center, USA
Exploring the Universe of Human Diseases
YU-CHUANG LI


 

Agriculture Biotechnology

THURSDAY, OCTOBER 23
15:45-17:45
Metabolic Flux, Protein Interaction and Transcription Regulation of Monolignol Biosynthesis in Populus trichocarpa
VINCENT L. CHIANG
North Carolina State University, USA

Suppressor Analysis of a Mutation Affecting Both RNA-directed DNA Methylation and Development in Arabidopsis
MARJORI MATZKE
Academia Sinica, Taiwan

A Protein Regulated by a Stress-inducible Promoter Enhances Root Growth and Abiotic Stress Tolerance in Rice without Yield Penalty
SU-MAY YU
Academia Sinica, Taiwan
Functional Analysis of Genes in Regulating the Flowering Time, Flower Formation and Senescence/abscission in Plants
CHANG-HSIEN YANG

FRIDAY, OCTOBER 24
15:45-17:45
Regulation of Phosphate Homeostasis: MicroRNA-mediated Surveillance of Phosphate Transport
TZYY-JEN CHIOU
Academia Sinica, Taiwan

Exploring Pseudomonas taiwanese Genome for Biocontrol Agents Against Rice Bacterial Blight Disease
MING-CHE SHIH
Academia Sinica, Taiwan

Immune Mechanisms in a Crustacean
KENNETH SÖDERHÄLL
Uppsala Universitet, Sweden

Recent Advances in Two Severe Shrimp Diseases, White Spot Syndrome Virus (WSSSV) and the Newly Emergent Acute Hepatopancreatic Necrosis Disease (AHPND)
Chu Fang Grace Lo
National Cheng Kung Univertsity, Taiwan


 

Synthetic Biology

FRIDAY, OCTOBER 24
15:45-17:45
CHUAN-HSIUNG CHANG
National Yang-Ming University, Taiwan

Engineering Proteins as Effective Therapeutic Nutrients
YING-JA CHEN
Pronutria, USA

Using Light to Characterize Bacterial Gene Circuit Dynamics
JEFFREY TABOR
Rice University, USA

Modular Construction of Synthetic Circuits Using TALE Transcriptional Repressors in Mammalian Cells
ZHEN XIE
Tsinghua University, China


 

Molecular Medicine and Drug Discovery

THURSDAY, OCTOBER 23
10:50-12:50
Discovery of Novel SHP-1 Agonists from Sorafenib from the Treatment of Hepatocellular Carcinoma
KUEN-FENG CHEN
National Taiwan University Hospital, Taiwan

Targeting ubiquitination pathways for cancer therapy
HUI-KUAN LIN
The University of Texas MD Anderson Cancer Center, USA

Mechanistic Studies of an Unusual C-O Bond Formation in Fosfomycin Biosynthesis
HUNG-WEN LIU
University of Texas MD Anderson Cancer Center, USA

Targeting Phenotypic Adaptation of Cancer Cells to Tumor Microenvironment
CHING-SHIH CHEN
The Ohio State University, USA


 

Antibody Therapeutics

THURSDAY, OCTOBER 23
10:50-12:50
Two-in-One Antibody: From Proof-of-Concept to Therapeutic Candidate
GERMAINE FUH
Genentech, Inc., USA

Construction and Use of Large Antibody Libraries in Mammalian Cells
JOHN MCCAFFERTY
University of Cambridge, UK

Next-Generation Sequencing and Structure-Based Design To Improve HIV-1-Neutralizing Antibodies
PETER KWONG
National Institutes of Health, USA

Deciphering Natural Antibody Responses with Phage-Displayed Synthetic Antibody Libraries
AN-SUEI YANG
Academia Sinica, Taiwan

FRIDAY, OCTOBER 24
15:45-17:45
Broadly Neutralizing Antibodies Define HIV Vaccine Targets
DENNIS BURTON
The Scripps Research Institute, USA

Counteracting Tumor Evasion of Antibody Immunity by a Novel Therapeutic Strategy
ZHIQIANG AN
The University of Texas, USA

IL-20 and IL-20 Receptor R1 Antibodies Protect Against Liver Fibrosis
MING-SHI CHANG
National Cheng-Kung University, Taiwan
Bispecific Antibody Targeting of PEGylated Medicines
STEVE ROFFLER



 

Cell Signaling, Molecular Basis of Diseases

WEDNESDAY, OCTOBER 22
15:45-17:45
How Tumor Cells Acquire Metastatic Traits
YIBIN KANG
Princeton University, USA

Pain and the Common East Asian Mutation in Aldehyde Dehydrogenase 2
DARIA MOCHLY- ROSEN
Stanford University, USA

Development of a Novel Therapeutic Peptide Targeting the Tumor Microenvironment
RANDOLPH WATNICK
Harvard Medical School, USA

Control of Metastatic Niche Formation by Src-SSeCKS Yin-Yang Regulation
IRWIN H. GELMAN
Roswell Park Cancer Institute, USA

FRIDAY, OCTOBER 24
10:50-12:50
Autophagic Lysosome Reformation
LI YU
Tsinghua University, China

Regulation of autophagy in Drosophila development and host defense
GUANG-CHAO CHEN
Academia Sinica, Taiwan

Discovering Protein-Protein Interactions within the Programmed Cell Death Network Using a Protein-Fragment Complementation Screen
ADI KIMCHI
Weizmann Institute of Science Rehovot, Israel

Molecular Control of Autophagy
SHARON A. TOOZE
London Research Institute, UK

SATURDAY, OCTOBER 25
10:50-12:50
Metabolic Stress Signaling by the JNK pathway
ROGER J. DAVIS
University of Massachusetts Medical School, USA

Connective Tissue Growth Factor Regulates Cancer Metabolism through Ubiquitination Pathway
CHENG-CHI CHANG
National Taiwan University, Taiwan

Dual-Specificity Phosphatases (DUSPs) in T-Cell Signaling and Autoimmune Diseases
TSE-HUA TAN
National Health Research Institutes, Taiwan

Control of Lipid Homeostasis and the Development of Obesity
PENG LI
Tsinghua University, China


 

Bioentrepreneurship, Translational Research

THURSDAY, OCTOBER 23
10:50-12:50
MING-CHU HSU
TaiGen Biotechnology, Taiwan

Mechanisms of EMT-induced Cancer Stemness
MUH-HWA YANG
National Yang-Ming University, Taiwan

hRAB37 GTPase, a novel metastasis suppressor in lung cancer
YI-CHING WANG
RaQualia's Vision: We Seek to Bring People Health and Happiness Through Innovative New Medicines
NAOKI TANI
RaQualia Pharma Inc., Japan

FRIDAY, OCTOBER 24
15:45-17:45
Regulatory Network in Dehydration-Stress Response and Its Application to Improve Drought Tolerance of Crops
KAZUO SHINOZAKI
RIKEN, Japan

Reprogramming of Primary Metabolism Facilitates Metabolic Engineering of Bioactive Compounds in Tomato Fruit
CATHIE R. MARTIN
John Innes Centre, UK

Leveraging Genomics Approaches to Enhance Food Security: Challenges and Opportunities
ROBERTO TUBEROSA
Universita Di Bologna

Biotechnology and Strategy for a Sustainable Grouper Aquaculture
HUEY-LANG YANG
National Cheng-Kung University, Taiwan


 

New and Emerging Subjects

THURSDAY, OCTOBER 23
15:45-17:45
NORDEN E. HUANG
National Central University, Taiwan

Coordinated Changes in Blood Flow and Bioenergy Associated with Tai Chi/Qigong and Traditional Chinese Medicine Therapies
SHIN LIN
University of California, Irvine, USA

Dynamical Biomarkers for Health and Disease
CHUNG-KANG PENG
National Central University, Taiwan

Nanomechanics of Intrinsically Disordered Proteins: Interplay of Force, Form and Function
KUAN WANG
Academia Sinica, Taiwan

FRIDAY, OCTOBER 24
10:50-12:50
KEITH DUNKER
Indiana University, USA

Protein Structural Dynamics One Tilt at a Time
YALE GOLDMAN
University of Pennsylvania, USA

Single Molecule Imaging Expanded to Macroscopic Level by Computer Simulation
TOSHIO YANAGIDA
Osaka University, Japan

Mechanobiology by Which Macrophages Pick Up Their Prey
VIOLA VOGEL
Eidgenössische Technische Hochschule Zürich, Switzerland


 

Epigenetics and Stem cells

WEDNESDAY, OCTOBER 22
10:50-12:50
ReguDNA Methylation and A Sweet Impact in Epigenetics and Cancer
LI-JUNG JUAN
Academia Sinica, Taiwan

DNA Methylation and Sweet Impact in Epigenetics and Cancer
HONG-KUI DENG
Peking University, China

Characterization of Non-Histone Lysine Methylation By A Synthetic Cofactor
YOICHI SHINKAI
RIKEN, Japan

3-Dimensional Chromatin Structure and Transcription Regulation
CHIA-LIN WEI
Lawrence Berkeley National Laboratory, USA









Registration open:
February 15
Abstract submission deadline:
August 31, 2014
Early bird registration:
August 31, 2014

YSP application:
April 30, 2014
YSP winner announcement:
June 10, 2014

 
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